This tabular data set represents select geochemical characteristics based on Olson geology types in surface or near surface geology (Olson, 2014) compiled for two spatial components of the NHDPlus version 2 data suite (NHDPlusv2) for the conterminous United States; 1) individual reach catchments and 2) reach catchments accumulated upstream through the river network. The select geochemical characteristics in surface or near surface geology are: 1) mean percentage of lithological calcium oxide (CaO), 2) mean lithological compressive strength, measured as uniaxial compressive strength (in megaPascals, MPa), 3) mean percentage of lithological phosphorus pentoxide (P2O5), 4) mean percentage of lithological potassium oxide (K2O), 5) mean percentage of lithological ferric oxide (Fe2O3), 6) mean percentage of lithological silicon dioxide (SiO2), 7) mean percentage of lithological sulfur (S), 8) mean hydraulic conductivity (in micrometers per second), and 9) mean percentage of lithological magnesium oxide (MgO). This dataset can be linked to the NHDPlus version 2 data suite by the unique identifier COMID. The source data for Geochemical Characteristics of the Conterminous United States was produced by Olson and Hawkins (U.S. Geological Survey, 2014). Reach catchment information characterizes data at the local scale. Reach catchments accumulated upstream through the river network characterizes cumulative upstream conditions. Network-accumulated values are computed using two methods, 1) divergence-routed and 2) total cumulative drainage area. Both approaches use a modified routing database to navigate the NHDPlus reach network to aggregate (accumulate) the metrics derived from the reach catchment scale. (Schwarz and Wieczorek, 2018).